Clinical Trials
Overview
Randomized clinical trials are the gold standard for evaluating the efficacy and safety of healthcare interventions. My research focuses on the development and application of statistical methods that improve trial design, analysis and reporting, contributing to more reliable and reproducible clinical research.
I am particularly interested in methodological challenges that arise in modern clinical trials and in translating statistical advances into practical tools for researchers.
Research Interests
- Design of randomized clinical trials
- Composite endpoints
- Survival analysis
- Sample size determination
- Statistical simulation
- Reporting guidelines for clinical research
Methodological Research
A major part of my work involves developing and evaluating statistical methods through simulation studies and applying them to real biomedical research. This includes the design of innovative approaches for complex trial settings and the assessment of their statistical performance.
Software
To facilitate the application of these methods, I develop open-source R packages that allow researchers to design studies, evaluate statistical methods and reproduce published analyses.
Collaboration
I collaborate with clinicians, epidemiologists and biomedical researchers in multidisciplinary projects, providing statistical expertise from study design to the interpretation and communication of results.
